SAMe, DMG and TMG must be kept in balance with folic acid and B12.ģ) Enhanced Nerve Function: When I take TMG, I notice a definite improvement in my handwriting. Please be aware of another potential problem with SAMe. This might have something to do with the increased methylation. (See page 305 of Braverman’s book on amino acids where he is talking about 3 grams of DMG.) Also he says that large doses of SAMe have been a problem with bi-polar depression. This has been observed with DMG, which is created from TMG. However, there is a possibility that large doses of TMG could have an opposite effect and cause depression. Bile emulsifies fat so it can be absorbed and bile carries toxins out of the liver into the intestines for disposal.Ģ) Improved Mood: The first time I took TMG, I noticed a definite improvement in mood, possibly because of the increase in SAMe levels. Another benefit is TMG’s ability to increase bile salts and bile production by the liver. Another benefit for the liver is the lipotropic nature of TMG - it helps get rid of fat deposits in the liver. The liver needs SAMe to perform many of its detoxification functions. According to him, one of TMG’s biggest advantages is that it greatly increases the production of SAMe. Here are a few properties of TMG that I find interesting.ġ) Improved Liver Function: One of my doctors likes to use TMG for his patients that have liver problems. You will find a lot of information about TMG, DMG and glycine in Dr. Some of its properties seem to relate to its ability to increase SAMe (S-Adenosyl-Methionine) levels, and some of its properties seem to relate to methylation and its ability to convert into glycine and DMG (di-methyl-glycine). Polly: TMG stands for tri-methyl-glycine. Pamela: What is TMG? I don’t think I have heard of this before. Since trying the TMG I’m happy again, and my joints feel good… so I guess it is working for me! SAMe is about a dollar a pill around here… whereas I got a large bottle of TMG (maybe 200 pills?) for $12.95. I have been taking TMG for about 2 weeks now. After about a week of taking nothing… and seeing the depression come slogging back into my consciousness, I tried TMG. I believe SAMe has helped me in all of the areas it is touted for: joint health, depression, and liver health. I took SAMe from June to the middle of December with excellent results.
Susan in Olympia: Hi Lynni! I think Polly just explained the difference here. Since TMG is a much cheaper supplement, it is worth trying first. Specially sealed capsules and refrigeration is best. I think someone may have said this on the forum before, but the quality and way SAMe is handled is real important. I’m wondering about a post where you said SAMe (S-Adenosylmethionine) and TMG (tri-methyl-glycine) are the same thing? Maybe you can illuminate? The good news I do know about SAMe is that it stimulates the synthesis of proteoglycans which are building blocks of joint cartilage and it also has anti-depressant qualities. Lynni: Hi Susan, I always enjoy your posts.
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